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Structural Biology Collaboration Examines "m6A" Messenger RNA Modification

A collaborative effort between Hasan Demirci (SLAC Bioscience/PULSE Institute) and the Puglisi group (Dept. of Structural Biology, Stanford) has recently been published in Nature Structural & Molecular Biology. The work, entitled "N6-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics", examined the effect of a common post-transcriptional modification in messenger RNA ("m6A"), whose precise role in ribosomal translation, if any, had been unclear.

New Journal Article Shows Surprising Finding About Particles Hit by LCLS X-rays

A recent paper on an LCLS experiment overseen by PULSE alum Christoph Bostedt (now at ANL/Northwestern) has been published, discussing an unexpected effect of ultrafast LCLS pulses on clusters of xenon atoms. This finding contributes to our understanding of the effects of the ultrafast, ultra-bright LCLS X-rays on particles being analyzed, in particular by revisiting a common assumption in LCLS experiments that particles will explode after receiving an XFEL pulse.

NPI Group Publishes Paper on New Sample Injector

An effort led by PULSE graduate student Raymond Sierra and research associate Hasan Demirci of the Non-Periodic Imaging group at PULSE has resulted in a recent publication at Nature Methods. Their work discusses a sample delivery mechanism developed by Sierra and the NPI group that can be used for biology experiments (e.g. serial femtosecond crystallography) at LCLS and other X-ray free electron lasers.

Aaron Lindenberg receives seed funding from Precourt Institute for Energy

In a recently-announced round of grant awards for research projects in clean energy, PULSE PI Aaron Lindenberg received a seed funding grant from the Precourt Institute of Energy.

The successful proposal is entitled "Mechanism of for broadband white-light emission from two-dimensional hybrid perovskites" Prof. Lindenberg and Prof. Hemamala Karundasa in the Department of Chemistry are PIs for this work.


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