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Photon Science Seminar: "Time-resolved crystallography captures light-driven DNA repair," TJ Lane, DESY
Sponsored by
SLAC
Event Details:
Wednesday, October 1, 2025
3:00pm - 4:00pm PDT
Location
B901-108AB Redtail Hawk Conference Room
Abstract
Photolyases employ light to repair DNA, specifically DNA damaged by sunlight. Due to its importance, spectroscopists have studied this life-preserving reaction for decades. Now, however, time-resolved crystallography is nailing down mechanistic questions that have eluded spectroscopy all that time. My talk will tell the story of how we witnessed DNA repair by a CPD photolyase using SFX and detail the mechanistic questions we resolved. I will conclude with a short perspective on what we are working on next, and why mechanistic details matter.
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